MEDISCH-GENETISCH CENTRUM ZUID-WEST NEDERLAND      

      - MGC -        

The Centre is an initiative of the Erasmus Medical Center and the Leiden University Medical Center

 

 

 

 

The 23rd MGC-Symposium

will be held Thursday September 19, 2013, in "Engels", Rotterdam

Symposia & Meetings:

The 10th annual symposium from the Centre for Medical Systems Biology (CMSB) will be on October 14-15, 2013 in the Stadsgehoorzaal in Leiden. The programme will highlight ten years of CMSB research. We will look back on all our achievements so far and discuss our future plans. More information will follow in the forthcoming months.

The 3rd IRB Barcelona PhD Student Symposium, a scientific meeting organized every two years by the student community at the Institute for Research in Biomedicine, Barcelona (IRB Barcelona). This third edition is entitled “The Clock of Life: cellular and molecular processes of development, ageing and disease” and will be held at La Pedrera in Barcelona on November 14-15, 2013. For more information see website.

To simplify the search for an interesting meeting: www.biomeeter.com .

This website gives an overview of conferences organized in all aspects of biology. It is open source so everybody can not only find but also add their meeting. It’s launched in April, 2012 and already contains over 400 conferences, a number that’s increasing every day.

All the added meetings are categorized so you can search both by keyword and category.

PCDI - Postdoc Career Development Initiative - is an organisation that aims at improving awareness of career planning and opportunities among postdocs, PhD students and their employers. We bring together scientists, universities and key players in the life science industry.

 

 

MGC Course Programme

You can enrol now for the following courses:

Course "Transgenesis, Gene Targeting and in vivo Imaging"

10 - 14 June, 2013

 Programme 

Registration via Boerhaave)

The course will consist of lectures covering general topics (i.e. generation of conventional transgenic mice by pronuclear injection, homologous recombination in embryonic stem cells, vector design, etc.), and specific topics (i.e. ES cell derivation, dedifferentation via iPS, etc.). In addition, a series of presentations will be given by renowned national and international scientists on specific applications of transgenesis, gene targeting, and embryonic stem cells in different areas of biomedical research.

Practical demonstrations will be given on the main and crucial steps in the generation of transgenic and KO mice, as well as on the principles of in vivo imaging.

The knowledge of the first 3 days of the course will be the basis to follow the presentations and (poster) discussions by invited speakers, post-docs, and PhD students on new and current issues in the 2-day international workshop on Innovative Mouse Models.

There is a minimum of 12 and a maximum of 30 places.  Should the course be oversubscribed, then places will be allocated on a first come, first serve basis. Deadline for registration May 31, 2013.

 

The course is free of charge for all PhD students from MGC, LUMC, and Erasmus MC. Participants from outside these organisations pay €250 per person for this course including lunch, coffee and tea.

In case of no show or cancellation after May 31, members of the MGC, LUMC, and Erasmus MC will be charged 50 euro, other participants have to pay the full price.

 

http://www.boerhaavenascholing.nl/pages/Boerhaave/Home

Course "Next Generation Sequencing data analysis" (7th ed)

28 - 30 August 2013, University Medical Center Utrecht

Programme  2013

Registration

The course aims at PhD students, postdocs and senior researchers who are interested in planning, or already working with next-generation sequencing. Currently available technologies as well as hardware and software solutions will be presented and discussed. The focus of the course will be on data and ways to analyse the data.

We only have facilities to accommodate 60 participants. If more than 60 people register a selection will be made based on the motivation field. Please include your NGS experience during registration. Those selected to participate in the course will be notified by August 1. Register before July 1, 2013.

Costs: PhD students from the MGC, CMSB, NBIC and CGDB are free of charge, other persons from the academic world pay 250 euro and 500 euro per person for corporate participants. Course is including lunches and handout.

In case of no show or cancellation after August 21, members of the MGC, LUMC, and Erasmus MC will be charged 50 euro, other participants have to pay the full price.

Announcements:

Course "Signal Transduction and Diseases"

13 - 16 May, 2013

LUMC

Programme  2013 (provisional)

 

Note: Course is cancelled!!

Next edition will be organized in spring 2014 under the title: 

From Molecular Pathogenesis to Targeted Therapy

 

The aim of this course is to give an overview of intracellular signalling processes that are activated by hormones, cytokines and growth factors, as well as state-of-the-art technology used to study signal transduction in vivo and in vitro. Teaching will occur by state-of-the-art lectures and interactive tutorial.

This is a combined course of Graduate Schools Medical Genetics Center South-West Netherlands and Molecular Medicine (MM).

In alternating years (e.g. 2010, 2012), MM offers a complementary course on Clinical genetics, Experimental Endocrinology and Immunoendocrinology.

There is a minimum of 16 and a maximum of 35 places.  Should the course be oversubscribed, then places will be allocated on a first come, first serve basis. Deadline for registration May 1, 2013.

http://www.boerhaavenascholing.nl/pages/Boerhaave/Home

Course "Development, Stem Cells and Disease"

 

(5 - 7 June, 2013) - course will be postponed

Probable new data October 2013

                           Programme  2011 (previous edition, including abstracts)

Registration (via Boerhaave)

The aim of this course is to discuss recent advances in our knowledge concerning the molecular and cellular mechanisms controlling the development of vertebrate embryos.

Stem cells: embryonic; somatic; cancer; plant

Patterning: fluorescence tagging; axis formation; face and limbs

Gene regulation: X-chromosome inactivation, tissue specific regulation

Signalling: Hedgehog, TGFβ, Notch, Wnt signalling.

Organ systems: Lung development; sex determination; muscle development; hematopoiesis; neuronal development; Axon-Glia interaction; Axon pathfinding.

 

There is a minimum of 15 and a maximum of 30 places.  Should the course be oversubscribed, then places will be allocated on a first come, first serve basis.

The course is free of charge for all PhD students from MGC, LUMC, Erasmus MC, and Developmental Biology (Utrecht). Participants from outside these organisations pay €200 per person for this course including lunch, coffee and tea.

In case of no show or cancellation after May 20, members of the MGC, LUMC, Erasmus MC, and Developmental Biology (Utrecht) will be charged 50 euro, other participants have to pay the full price.

 

http://www.boerhaavenascholing.nl/pages/Boerhaave/Home

Courses organized by MolMed:

 

The following courses are on the MolMed website and open for registration:
 

5th Symposium & master classes on Mucosal Immunology: Cytokines and border patrol
13 - 14 May 2013
As a continuation of four prior very successful Symposia and workshops on Mucosal Immunology, organised by the Erasmus Postgraduate School Molecular Medicine in 2004, 2006 2008 and 2011, a fifth Symposium and workshops will be held in May 2013. The committee has invited nationally and internationally leading scientists to give the keynote lectures regarding mucosal humoral immunity and address the controversies within the field. In particular, we will welcome:
• Dr. Denise Kelly
• Prof. Bart Lambrecht
• Dr. Samuel Huber
• Prof. Jim di Santo
• Prof. Shigeo Koyasu
• Prof. Warren Leonard
• Prof. Sebastian L. Johnston
• Dr. Tom Cupedo
The symposium will take one day (Monday May 13h). Based on the previous symposia we expect up to 100 or more attendees from all over the Netherlands and Belgium. The second day (Tuesday May 14th) will be used for workshops. The keynote speakers will join the workshops for all attending PhD candidates and post docs, who will present their own work. In these sessions, the presented data will be discussed under the guidance of the Lecturer and one staff scientist from our research school. As such, these sessions will be thoroughly prepared.
Full program and registration: www.molmed.nl
 

Workshop on Basic data analysis on gene expression arrays together with Ingenuity (BAGE)
15 - 17 May 2013 (new dates, postponed from March)
We are organizing once again this three days workshop on Basic data analysis of gene expression arrays. As for the previous edition, the first day will be lectures and practicals organized in collaboration with the dept. of Bioinformatics, and for the 2nd and 3rd day Ingenuity will come with a few trainer, to discuss IPA visualization and NGS with Ingenuity..
For more information aand registration: www.molmed.nl
 

The course Basic and Translational Oncology
27-31 May 2013
This course provides a comprehensive introduction to the field of translational cancer research. It is meant for PhD students and postdocs in MolMed and MGC, but others (e.g., students and technicians of LUMC and Erasmus MC) are welcome too. The program is set up logically in 5 steps, one step a day: 1. Pathology, diagnostics & pathways in cancer; 2. Biology of the cancer cell: Genetics & Epigenetics; 3. Genetic susceptibility, invasion & metastasis; 4. Clinical practice: diagnostics & targeted therapies; 5. Translational research, epidemiology of cancer, cancer data in research & end-of-life interventions.
Furthermore, we are proud to announce again some famous keynote speakers. For the first time Doug Easton (University of Cambridge, Strangeways Research Lab); and again Piet Borst, Jos Jonkers and René Bernards (NCI). All their lectures will be announced more widely.
Like last year, the program is enriched with journal clubs (JC’s) and lab sessions with course speakers. Publications to be discussed are announced one month in advance to all participants. We expect you to prepare these before the course starts. All participants are expected to give a short presentation during one of the the JC’s. These will be organised during the first 2 days of the course.
More information and registration: www.molmed.nl

Course on Molecular Diagnostics VIII
3 - 4 June 2013, Erasmus MC
This course will bring the state-of-the-art of these areas of the Molecular Diagnostics, and is meant for translational researchers as well as doctors and medical specialists operating outside of their initial field of research. But also PhD-students and technicians are welcome.
The course starts with 3 presentations on basic molecular techniques: PCR and real-time, quantitative PCR; DNA sequencing; basic technologies; Next generation Sequencing (NGS); followed by 1,5 day on the applications in various fields.
More information, full program and registration: www.molmed.nl

Analysis of microarray and RNA Seq expression data using R/BioC and web tools
17 - 21 June 2013
Five days hands-on computer course for biological and clinical researchers whose research involves experiments that generate gene expression data. The course focuses on microarray data, but some concepts may be applicable to next-generation sequencing gene expression data, or other types of genomics data measured on microarrays. Most of the speakers (and therefore examples) have a biomedical background. Software packages used are mostly freeware, including the statistical software R, Bioconductor, Cytoscape and web tools. The only commercial tool used is Spotfire. The total number of participants is limited to 40.
More information and registration: www.molmed.nl
 

Translational Imaging Workshop by AMIE: From mouse to man
24 - 27 September 2013
The programme Applied Molecular Imaging at Erasmus MC (AMIE) provides a platform for scientists interested in imaging technology and molecular imaging in general. The aim of this 4-day workshop is to give a broad introduction into preclinical and translational Molecular Imaging techniques and their applications in biology and medicine. This workshop is designed for PhD-students and researchers in one of the Erasmus Postgraduate Schools, but PhD students and researchers from other universities are also welcome.
More information and registration: www.molmed.nl
 

Courses organised by Boerhaave CME:

On the 'Boerhaave CME (Continuing Medical Education)' website several courses for PhD students and other employees of the LUMC are announced:

 

- Introduction Genetic Epidemiology:  (once a year)

This intensive three day course will provide an introduction in genetic epidemiology. A large part of the day will be devoted to paper and computer exercises. Participants will gain practical experience by analyzing various data sets using SPSS or STATA.

 

- Design, Management & Analysis of Clinical trials: (once a year)

In this course, issues regarding the design, implementation and analysis of clinical trials will be considered. Topics include randomization and blinding, sample size calculations, flexible designs (interim analyses and stopping rules), cross-over trials, data monitoring and safety committees, data management and of course the statistical analyses based on the design chosen. We will also cover some aspects of reporting the design and outcome of clinical trials in scientific journals as well as Good Research Practice in general.
 

- Advanced Genetic Association Analysis: (once a year)

This up to date course in genetic association analysis includes now highly relevant topics such as the analysis of imputed genotypes in GWAS, genetic pathway analysis using GWAS data and the statistical analysis of rare variants detected by next generation sequencing. Participants have to bring their own laptop for practicals.
 

- Regression Analysis: (once a year)

This course considers both theoretical backgrounds and practical aspects of modeling data with regression models. The focus is on linear and logistic regression models, although other models, like Poisson models or non linear regression models for continuous data will also be discussed. All statistical methods are practiced, using SPSS.
 

- Using R in Data Analysis: (once a year)

R is an environment for statistical computing and graphics. Its flexibility, allied to the fact that it is open-source and free, have made it an ideal repository for implementations of statistical analysis methods, both classic and new. However, it has a steep learning curve, due partly to its using a command-line type of user interface, rather than the usual pull-down menus of most commonly used statistical packages such as SPSS. This 3-day course aims at helping researchers climb this curve, enabling them to perform basic data analysis and graphic displays at the end of the course, as well as giving a platform from which they can deepen their R knowledge later on if necessary.
 

- Dealing with Conflicting Demands: (once a year)

The life of a scientist presents many conflicting demands in any phase of the scientific career, but certainly in the last phase of a PhD study. The course ‘Dealing with Conflicting Demands’ builds on Dilemma Theory created in the 1980s by Prof. Charles Hampden-Turner (Cambridge, UK). Over the last decade the methodology has been further developed into a practical skill, used by staff of large and small corporations, including private and public research institutions. The skill to reconcile conflicting demands has proven key to being successful in a complex and competitive environment, such as your current and future working life as a scientist or any other professional environment.
 

- Repeated measurements: (once a year)

The course covers statistical methods to be used in the situation where one or more outcome variables are repeatedly measured in time on the same experimental unit.

 

- Basic methods and reasoning in biostatistics: (once a year)

The AIO courses in Biostatistics consist of two series: “A:basic” and “B:advanced”. Participants in part B should have followed part A or have acquired the skills trained in part A in another way. Part B as of 2009 consists of a series of separate courses, each dedicated to a specific subject.
Part A is a single one week course:
In this course we will cover basics of biostatistics and the participants will learn how to analyze problems in clinical research using SPSS. Subjects covered are among others: methodology of statistical analysis; causal inference; descriptive statistics; the principle of statistical estimation and testing; cross tabulation and chi-square test; Student t-test and the correspondence with non-parametric counterparts; simple regression and correlation; introduction to analysis of variance; interpretation of observational data; bias and confounding; interaction.
 

 

General information:

Download the booklet with the teaching programme for PhD students, version 2012-2013

For new PhD students: Download the forms for Coaching Group and Teaching Plan

Download MGC bulletin 47 (September 2012), MGC bulletin 46 (March 2012)

Website of Leiden University on teaching for PhD students: English or Dutch. [Courses on Research management; Career counseling; Academic writing; Writing grants, proposals and beyond; Faster reading and Memory-improvement; Creative thinking; Academic presentation / Presentation of academic work; Orientation in policymaking; Orientation on Management]

 

The MGC Institutes

Het MGC secretariaat is gevestigd op

de afdeling Toxicogenetica te Leiden.

TEL 071-5269600; FAX 071-5268284  

Directie secretaris: Dr. M.J.M. Nivard 071-5269605  

e-mail: nivard@lumc.nl

 

De MGC instituten:

Instituut Celbiologie

Erasmus Universiteit Rotterdam

Postbus 2040, 3000 CA Rotterdam

010-7043593

hoofd: Prof.Dr. F.G. Grosveld  (voorzitter MGC bestuur)

 

Centrum voor Humane en Klinische Genetica

Leiden Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden

071-5269400

hoofd: Prof.Dr. S.M. van der Maarel 

Prof. Dr. G.J.B. van Ommen (secretaris MGC bestuur)

Instituut Genetica

Erasmus Universiteit Rotterdam

Postbus 2040, 3000 CA Rotterdam

010-7043199

hoofd: Prof.Dr. J.H.J. Hoeijmakers (lid MGC bestuur)

Afd. Toxicogenetica

Leids Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden

071-5269600

hoofd: Prof.Dr. L.H.F. Mullenders (lid MGC bestuur)  

LACDR (Leiden/Amsterdam Center for Drug Research) - Toxicology group

Universiteit Leiden

P.O. Box 9502, 2300 RA Leiden

071-5276223

hoofd: Prof.Dr. B. van de Water (lid MGC bestuur)  

Instituut Klinische Genetica

Erasmus Universiteit Rotterdam

Postbus 2040, 3000 CA Rotterdam

010-7043198

hoofd: Prof.Dr. R.M.W. Hofstra (lid MGC bestuur)

Andere instituten/groepen binnen het MGC

Moleculaire Celbiologie (Prof. Dr. H.J. Tanke & Prof. Dr. A.K. Raap, Prof. Dr. J. Noordermeer & Dr. L. Fradkin, Prof. Dr. R. Hoeben, Prof. Dr. J.A. Maassen, Prof. Dr. P. ten Dijke)

Neurologie, groep neurogenetica, LUMC (Prof. Dr. R.A.C. Roos, Prof. Dr. J.J.G.M. Verschuuren, Prof. Dr. M.D. Ferrari)

Huid- en geslachtsziekten, groep erfelijke melanomen, LUMC (Prof. R. Willemze, Prof. Dr. W. Bergman, Dr. F. de Gruijl, Dr. N.A. Gruis)

Pathologie: moleculaire tumorpathologie, LUMC (Prof. Dr. P.C.W. Hogendoorn, Prof. J.V.M.G. Bovee, Prof. Dr. J. Morreau, Prof. Dr. P. Devilee)

Medische Statistiek, LUMC (Prof. Dr. T. Stijnen, Prof. Dr. P.E. Slagboom)

Anatomie en Embryologie, LUMC (Prof. Dr. C.L. Mummery)

Instituut Pathologie, groep Fodde, Erasmus MC (Prof. Dr. R. Fodde)

Erasmus Optical Imaging Centre (OIC), Department of Pathology, Erasmus MC (Prof. Dr. A. B. Houtsmuller)

Kinderheelkunde, Ontwikkelingsbiologie groep, Erasmus MC (Prof. Dr. D. Tibboel)

Genetische Epidemiologie, Erasmus MC (Prof. Dr. C.M. van Duijn)

Afd. Voortplanting en Ontwikkeling, Erasmus MC (Prof. Dr. J.A. Grootegoed)

Forensische Moleculaire Biologie, Erasmus MC (Prof. Dr. M. Kayser)

Bioinformatica, Erasmus MC (Prof. Dr. P. van der Spek)

Biochemie, Erasmus MC (Prof. Dr. P. Verrijzer)

 

   [n.b. verbeteringen voor deze lijst gaarne doorgeven aan het secretariaat]

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Revised: June 13, 2013