MEDISCH-GENETISCH CENTRUM ZUID-WEST NEDERLAND      

      - MGC -        

The Centre is an initiative of the Erasmus Medical Center and the Leiden University Medical Center

 

 

Symposia & Meetings:

Third International One Health Conference 2015 Prevention at the Source will be held in the city of Amsterdam, the Netherlands from 15-18 March 2015  (http://www.iohc2015.com). Please observe the deadline of October 1st for abstract submission.

To simplify the search for an interesting meeting: www.biomeeter.com .

This website gives an overview of conferences organized in all aspects of biology. It is open source so everybody can not only find but also add their meeting. It’s launched in April, 2012 and already contains over 400 conferences, a number that’s increasing every day.

All the added meetings are categorized so you can search both by keyword and category.

Avans Hogeschool Breda organiseert een aantal cursussen:

Principles, parameters and applications of PCR, Datum: 7 april 2015, Kosten: €400,-, Website: http://www.alsavans.nl/avans-training-2545.htm

Real-time PCR in molecular diagnostics, Datum: 8-10 april 2015, Kosten: €900,-, Website: http://www.alsavans.nl/avans-training-2548.htm

Introduction to Next Generation Sequencing; technologies and data analysis, Datum: 14-17 april 2015, Kosten: € 1100,-, Website: http://www.alsavans.nl/avans-training-2542.htm

PCDI - Postdoc Career Development Initiative - is an organisation that aims at improving awareness of career planning and opportunities among postdocs, PhD students and their employers. We bring together scientists, universities and key players in the life science industry.

he 13th edition of  the PCDI Postdoc Retreat, targeting postdocs and final-stage PhD students in Life Sciences will be on 25 - 27 March 2015. This course is about professional and career development: ae you fully making use of your talents? What future matches your drives and skill set? What priorities do you need to set to maximise your potential? Read more...

 

 

MGC Course Programme

You can enrol now for the following courses:

Course 'Linux and basic scripting'

26 and 27 January, 2015, Hogeschool Leiden

Program 2015 (version December 30, 2014)

The course is designed for researchers, including PhD students and postdocs, who frequently handle large datasets or large numbers of files and who need a more efficient way of working with such data.

For registration send an email to Nivard@lumc.nl not later than January 22, 2015.  

Course 'Technology Facilities'

9-11 February, 2015, LUMC

Technology facilities program 2014

Registration

The course will deal with three topics:

Day 1 - Genomics and Transcriptomics

     Organizers: Dr. W. van IJcken, Erasmus MC, Rotterdam and Dr. H.P.J. Buermans, LUMC, Leiden

Day 2 - Proteomics

    Organizers: Dr. J. Demmers, Erasmus MC, Rotterdam and Dr. P. Hensbergen, LUMC, Leiden

Day 3 – Imaging

     - Live cell imaging

    Organizers: Prof. Dr. A. B. Houtsmuller and Dr. W.A. van Cappellen, Erasmus MC, Rotterdam

     - In vivo imaging – whole body optical imaging and MRI technology

    Organizer: Prof. Dr. C. Lowik, LUMC, Leiden

 

The course is meant for PhD students, or technicians, post-docs who just started their research or are not familiar with the different topics. One can subscribe also for only one or two days.

There is a minimum of 20 and a maximum of 50 places.

The course is free of charge for all personnel from MGC. Participants from outside these departments pay €200 for this course including lunch. Registration costs for a single day is €100. Deadline for registration January 26, 2015

Course 'Safely working in the Laboratory'

Date cancelled (was 5 March, 2015)

New date: Thursday April 2, 2015 in room J1-117, LUMC

Course is fully booked; registration is closed

This course is mandatory for all PhD students working within a department associated with MGC. This edition of the course will be in English; the Dutch version is expected to be given in December 2015.

The course is free of charge for all MGC personnel

Workshop  ’Share your biotechnology research with a broad audience’

16 en 30 March, 2015, LUMC

A training course on 'how to share your biotechnology research with a broad audience, like patients, clients, journalists or investors'. How do you go about this? What should you tell and how to make sure that the reader doesn’t lose quickly interest after the first sentences. 

In the workshop Marianne Heselmans and Astrid Smit – two experienced science journalists - provides you with tools to do this. They will teach you to understand the reader, to discover your own appealing story, to write this down in a clear way. The workshops are practical. You get started quickly, after a theoretical introduction. Smit and Heselmans prefer to work with your own texts. These may be blogs, websites, articles for specialist journals,  posters, press releases or presentations. You work on an assignment already before and also between the two workshop sessions.

The workshop will be given at the LUMC in Leiden on 16 and 30 March, 2015 from 13:30 - 17:30 h.  The workshops are meant for phd’s and postdoc’s and is free for researchers of MGC. There is a maximum of 12 and a minimum of 7 participants.

Selection is on first-come, first-served basis.  

 For registration send an email to Nivard@lumc.nl not later than February 28, 2015.  

For more information go to www.deperskamer.eu.

Announcements:

Courses organized by MolMed

 

MS Excel: Basic workshop

20 January

One-day practical workshops on the use of Excel. This workshop is prerequisite for the Advanced Excel Workshop. This course is given by a very experienced, external teacher.

For more information about our Excel and Access courses and for registration: www.molmed.nl

 

 The Ensembl Workshop

22 -23 January 2015

This two-day workshop offers participants the possibility of gaining lots of hands-on experience in the use of the Ensembl genome browser, and provides them with the necessary background information. The workshop is primarily targeted at wetlab researchers.

Giulietta Spudich from EMBL's European Bioinformatics Institute (EBI) will give this workshop, together with members of the Ensembl Comparative Genomics and Ensembl Variation teams.

The Ensembl project (see at: http://www.ensembl.org) provides a comprehensive and integrated source of annotation of, mainly vertebrate, genome sequences. Access to genes, sequences, homologues, SNPs and other short sequence variation, and potential gene regulation regions will be covered in this course.

Most modules consist of a presentation, followed by the opportunity to do exercises. Participants are encouraged to bring problems/questions about their research to try to tackle these during the workshop using Ensembl.

Hands-on workshop on the genome browser Ensembl given by teachers from the European Bioinformatics Institute. (www.ensembl.org)

For more information and registration: www.molmed.nl

 

Microscopic Image Analysis: From Theory to Practice 

26-27 January 2015

Practical course for PhD students and Postdocs who would like to deepen their understanding of image analysis methods and learn how to use them. No prior knowledge of image processing is required.

For more information, program and registration: www.molmed.nl

  

Adobe Photoshop & Illustrator, Indesign Workshops

27, 28 January, 10, 24, 25 February 2015

Hands-on workshop on the Adobe programs Photoshop, Illustrator and Indesign CS6. These programs are used for image enhancement and for drawing high quality graphs, tables and other figures. These are also freely available at the Erasmus MC on all Som-pc‘s. These can also be purchased at a very low price via surfspot.nl

Due to new financial regulations of the board of the school, this course is no longer free for MolMed-members; however, you can pay for participation at 50% discount from the ‘Persoonlijk Budget’.

For more information and registration: www.molmed.nl

  

Course on Basic and Translational Oncology

2-6 February 2015

This year’s course features keynote lectures by visiting professors invited by the Daniel den Hoed Foundation: Prof.dr. Norman Maitland and Prof.dr. Charles Swanton who will also give a master class.

Also from NCI Piet Borst and Jos Jonkers will give keynote lectures. It is possible to only attend these keynote lectures; then registration is not necessary.

This course provides a comprehensive introduction to the field of translational cancer research.

The program is set up logically in 5 steps, one step a day: 1. Pathology, diagnostics & pathways in cancer; 2. Biology of the cancer cell: Genetics & Epigenetics; 3. Genetic susceptibility, invasion & metastasis; 4. Clinical practice: diagnostics & targeted therapies; 5. Translational research, epidemiology of cancer, cancer data in research & end-of-life interventions.

Journal clubs : the program is also enriched with journal clubs (JC’s) and lab sessions with the speakers.

For more information and registration: www.molmed.nl

  

MS Access: Basic workshop

12 February

One-day practical workshops on the use of Access. This workshop is prerequisite for the Advanced Access Workshop. This course is given by a very experienced, external teacher.

For more information about our Excel and Access courses and for registration: www.molmed.nl

 

Ingenuity Pathway Analysis (IPA) Workshop

17 February 2015

One-day practical computer workshop on IPA taught by teachers from Ingenuity.

A detailed program will follow, but it is already possible to register via: www.molmed.nl

 

CLC Workbench / Ingenuity Variant Analysis Workshop

18 February 2015

One-day practical computer workshop on CLC Workbench taught by teachers from Ingenuity.

A detailed program will follow, but it is already possible to register via: www.molmed.nl

 

MS Access: Advanced workshop

12 February

One-day practical workshops on the use of Access. In this workshop you will design and create a new Access database; improve queries, create advanced forms, and reports; and integrate Access 2010 with other applications. This course is given by a very experienced, external teacher. Taking first the basic Access Workshop is required.

For more information about our Excel and Access courses and for registration: www.molmed.nl

 

MS Excel: Advanced workshop

12 February

One-day practical workshops on the use of Excel. In this workshop you will use advanced formulas and work with various tools to analyze data in spreadsheets. You will also organize table data, and enhance the look and appeal of workbooks. Enhancing productivity and efficiency by streamlining the workflow with an introduction into Macro’s. This course is given by a very experienced, external teacher. Taking first the basic Excel Workshop is required.

For more information about our Excel and Access courses and for registration: www.molmed.nl

 

Biomedical English Writing Course for MSc and PhD-students

10 & 31 March, 21 April & 12 May.

Course of four sessions on writing a scientific article. Participants should ensure that they have time to prepare the various sections of a scientific paper or a lab work report, or to revise an already available manuscript. If your work has not advanced to this point, you should then participate in a later course.

For more information and registration: www.molmed.nl

 

Partek Course on Microarray and NGS Analysis

24- 25 March 2015

Hands-on computer workshop taught by teachers from Partek on Microarray and NGS Analysis with Partek software.

You can register via our website: www.molmed.nl

  

Browsing Genes and Genomes with UCSC: Basic & Advanced

1 & 2 April 2015

This workshop will show how the UCSC Genome Browser is used to view multiple data sets at a variety of scales, from single-base to whole-genome. Attendees will learn browser navigation and an overview of the paradigm for data display. Selected datasets will be presented, such as UCSC Genes (a gateway to a large number of data sources) OMIM and Comparative Genomics tracks. Attendees will also learn about search, and about sharing information with others via Custom Tracks, the Sessions tool and the pdf-export function. Also presented will be the most recent tools, including bigBed and bigWig file formats, display of BAM files from high-throughput sequencing and data hubs.

Practical exercises will include Table Browser queries; using Custom Tracks; BLAT, a program for sequence alignment on the genome and the isPCR tool to test the uniqueness and predicted product from PCR (including on RNAs).

For more information and registration: www.molmed.nl

 

Research management for PhD-students

13 & 27 May 2015

Popular 2-days course on research management skills for PhD-students: - Time management; - Negotiating; - Yearly reviews (‘jaargesprekken’); and - Project management.

Full course attendance is necessary. There is place for 12 participants.

Due to a change in financial regulation this course is no longer free for MolMed-participants. Participation can for example by paid by your ‘persoonlijk budget’. However, it is still a very good course that is highly recommended by previous participants and will save you stress and frustration in your PhD-career.

For more information and registration: www.molmed.nl

 

Courses organised by Boerhaave CME

On the 'Boerhaave CME (Continuing Medical Education)' website several courses for PhD students and other employees of the LUMC are announced:

 

- Introduction Genetic Epidemiology:  (once a year)

This intensive three day course will provide an introduction in genetic epidemiology. A large part of the day will be devoted to paper and computer exercises. Participants will gain practical experience by analyzing various data sets using SPSS or STATA.

 

- Design, Management & Analysis of Clinical trials: (once a year)

In this course, issues regarding the design, implementation and analysis of clinical trials will be considered. Topics include randomization and blinding, sample size calculations, flexible designs (interim analyses and stopping rules), cross-over trials, data monitoring and safety committees, data management and of course the statistical analyses based on the design chosen. We will also cover some aspects of reporting the design and outcome of clinical trials in scientific journals as well as Good Research Practice in general.
 

- Advanced Genetic Association Analysis: (once a year)

This up to date course in genetic association analysis includes now highly relevant topics such as the analysis of imputed genotypes in GWAS, genetic pathway analysis using GWAS data and the statistical analysis of rare variants detected by next generation sequencing. Participants have to bring their own laptop for practicals.
 

- Regression Analysis: (once a year)

This course considers both theoretical backgrounds and practical aspects of modeling data with regression models. The focus is on linear and logistic regression models, although other models, like Poisson models or non linear regression models for continuous data will also be discussed. All statistical methods are practiced, using SPSS.
 

- Using R in Data Analysis: (once a year)

R is an environment for statistical computing and graphics. Its flexibility, allied to the fact that it is open-source and free, have made it an ideal repository for implementations of statistical analysis methods, both classic and new. However, it has a steep learning curve, due partly to its using a command-line type of user interface, rather than the usual pull-down menus of most commonly used statistical packages such as SPSS. This 3-day course aims at helping researchers climb this curve, enabling them to perform basic data analysis and graphic displays at the end of the course, as well as giving a platform from which they can deepen their R knowledge later on if necessary.
 

- Dealing with Conflicting Demands: (once a year)

The life of a scientist presents many conflicting demands in any phase of the scientific career, but certainly in the last phase of a PhD study. The course ‘Dealing with Conflicting Demands’ builds on Dilemma Theory created in the 1980s by Prof. Charles Hampden-Turner (Cambridge, UK). Over the last decade the methodology has been further developed into a practical skill, used by staff of large and small corporations, including private and public research institutions. The skill to reconcile conflicting demands has proven key to being successful in a complex and competitive environment, such as your current and future working life as a scientist or any other professional environment.
 

- Repeated measurements: (once a year)

The course covers statistical methods to be used in the situation where one or more outcome variables are repeatedly measured in time on the same experimental unit.

 

- Basic methods and reasoning in biostatistics: (once a year)

The AIO courses in Biostatistics consist of two series: “A:basic” and “B:advanced”. Participants in part B should have followed part A or have acquired the skills trained in part A in another way. Part B as of 2009 consists of a series of separate courses, each dedicated to a specific subject.
Part A is a single one week course:
In this course we will cover basics of biostatistics and the participants will learn how to analyze problems in clinical research using SPSS. Subjects covered are among others: methodology of statistical analysis; causal inference; descriptive statistics; the principle of statistical estimation and testing; cross tabulation and chi-square test; Student t-test and the correspondence with non-parametric counterparts; simple regression and correlation; introduction to analysis of variance; interpretation of observational data; bias and confounding; interaction.
 

 

General information:

Download  the booklet with the teaching programme for PhD students, version 2014-2015

For new PhD students: Download the forms for Coaching Group and Teaching Plan

Download MGC bulletin 51 (September 2014),  MGC bulletin 50 (April 2014), 49 (September 2013)

Website of Leiden University on teaching for PhD students: English or Dutch. [Courses on Research management; Career counseling; Academic writing; Writing grants, proposals and beyond; Faster reading and Memory-improvement; Creative thinking; Academic presentation / Presentation of academic work; Orientation in policymaking; Orientation on Management]

 

The MGC Institutes

Het MGC secretariaat is gevestigd op

de afdeling Humane Genetica, LUMC, Leiden.

TEL 071-5269600; FAX 071-5268284  

Directie secretaris: Dr. M.J.M. Nivard 071-5269605  

e-mail: nivard@lumc.nl

 

De MGC instituten:

Instituut Celbiologie

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam

010-7043593

hoofd: Prof.Dr. D. Huylebroeck (lid MGC bestuur)

 

Afd. Humane Genetica

Leiden Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden

071-5269400

hoofd: Prof.Dr. S.M. van der Maarel  (lid MGC bestuur)

Instituut Genetica

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam

010-7043199

hoofd: Prof.Dr. J.H.J. Hoeijmakers (lid MGC bestuur)

Afd. Humane Genetica

Leids Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden

071-5269600

Prof.Dr. L.H.F. Mullenders (voorzitter MGC bestuur)

LACDR (Leiden/Amsterdam Center for Drug Research) - Toxicology group

Universiteit Leiden

P.O. Box 9502, 2300 RA Leiden

071-5276223

hoofd: Prof.Dr. B. van de Water (lid MGC bestuur)  

Instituut Klinische Genetica

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam

010-7043198

hoofd: Prof.Dr. R.M.W. Hofstra (secretaris MGC bestuur)

Andere instituten/groepen binnen het MGC

Moleculaire Celbiologie (Prof. Dr. H.J. Tanke & Prof. Dr. A.K. Raap, Prof. Dr. J. Noordermeer & Dr. L. Fradkin, Prof. Dr. R. Hoeben, Prof. Dr. J.A. Maassen, Prof. Dr. P. ten Dijke)

Neurologie, groep neurogenetica, LUMC (Prof. Dr. R.A.C. Roos, Prof. Dr. J.J.G.M. Verschuuren, Prof. Dr. M.D. Ferrari)

Huid- en geslachtsziekten, groep erfelijke melanomen, LUMC (Prof. R. Willemze, Prof. Dr. W. Bergman, Dr. F. de Gruijl, Dr. N.A. Gruis)

Pathologie: moleculaire tumorpathologie, LUMC (Prof. Dr. P.C.W. Hogendoorn, Prof. J.V.M.G. Bovee, Prof. Dr. J. Morreau, Prof. Dr. P. Devilee)

Medische Statistiek, LUMC (Prof. Dr. T. Stijnen, Prof. Dr. P.E. Slagboom)

Anatomie en Embryologie, LUMC (Prof. Dr. C.L. Mummery)

Erasmus Optical Imaging Centre (OIC), Department of Pathology, Erasmus MC (Prof. Dr. A. B. Houtsmuller)

Kinderheelkunde, Ontwikkelingsbiologie groep, Erasmus MC (Prof. Dr. D. Tibboel)

Genetische Epidemiologie, Erasmus MC (Prof. Dr. C.M. van Duijn)

Afd. Voortplanting en Ontwikkeling, Erasmus MC (Prof. Dr. J.A. Grootegoed)

Forensische Moleculaire Biologie, Erasmus MC (Prof. Dr. M. Kayser)

Bioinformatica, Erasmus MC (Prof. Dr. P. van der Spek)

Biochemie, Erasmus MC (Prof. Dr. P. Verrijzer)

 

   [n.b. verbeteringen voor deze lijst gaarne doorgeven aan het secretariaat]

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Revised: January 16, 2015