- MGC -        

The Centre is an initiative of the Erasmus Medical Center and the Leiden University Medical Center



Publieksmiddag 'Wijzer over DNA'

Museum Boerhaave, zondag 8 november 2015


Voor het negende achtereenvolgende jaar wordt er in Leiden in Museum Boerhaave een publieksvoorlichtingmiddag georganiseerd over ‘Genetica’ onder de noemer ‘Wijzer over DNA’.

Toegang is gratis [koffie, thee en borrel inbegrepen].


Er is plaats voor 125 personen. Graag vooraf inschrijven

Programma Wijzer over DNA


Inschrijving publieksmiddag Wijzer over DNA


Symposia & Meetings:

Nuclear Receptor Research Network meeting, 03-12-2015, Leiden

On December 3rd 2015, the Nuclear Receptor Research Network (NRRN) is organising the 8th Benelux Nuclear Receptor meeting at the Boerhaave museum in Leiden. The latest advances on nuclear receptor (NR) research will be discussed.

Registration deadline: November 1st.

For more information visit the website

To simplify the search for an interesting meeting: .

This website gives an overview of conferences organized in all aspects of biology. It is open source so everybody can not only find but also add their meeting. It’s launched in April, 2012 and already contains over 400 conferences, a number that’s increasing every day.

All the added meetings are categorized so you can search both by keyword and category.

Avans University of Applied Sciences organiseert twee cursussen

Titel: Medische Immunologie, Datum: 17 september – 26 november 2015 (om 19.00-21.30), Locatie: Erasmus MC, Rotterdam, Kosten: €950,- (inclusief cursusmateriaal), Website:

 Titel: Flowcytometrie, van kalibratie tot applicatie, Datum: 10, 17 en 24 november 2015 (om 16.00-18.30), Locatie: Erasmus MC, Rotterdam, Kosten: €600,- (inclusief theoretisch naslagwerk), Website:

PCDI - Postdoc Career Development Initiative - is an organisation that aims at improving awareness of career planning and opportunities among postdocs, PhD students and their employers. We bring together scientists, universities and key players in the life science industry.

From 28 - 30 October PCDI organises the 14th edition of the PCDI Postdoc Retreat. At this course you will literally be taken out of your academic environment to spend dedicated time to think about your future, improve your skills and learn about the many aspects that contribute to success. The programme offers a combination of lectures by inspiring PhD graduates, training sessions, a forum discussion with opinion leaders and energising networking sessions, all aimed at broad career and professional development. This edition especially targets postdocs and final stage PhD students in Science, Technology, Engineering, Maths (STEM). For more information about the course read on



MGC Course Programme

You can enrol now for the following courses:

Course "Next generation sequencing (NGS) data analysis"

9th edition, at the University Medical Centre Groningen

September 28–30, 2015


Provisional program NGS 2015

This course aims at PhD students, postdocs, and senior researchers who are interested in, planning, or already working with next-generation sequencing. We welcome researchers from both the genomics and bioinformatics fields. Currently available technologies as well as hardware and software solutions will be presented and discussed. The focus of the course will be on the data and ways to analyse these.



Registration for PhD students from the MGC and GSMS is free of costs. Members of BioSB pay € 175,00. Participation fee for participants of the academic world is € 250,00 and participation fee for people outside the academic world is € 500,00.

Register before September 14, 2015. We only have facilities to accommodate 60 participants. All registrants have to fill in their motivation and experience in the free text field of the web form. When we receive more registrations than available positions selection will be made on basis of motivation and experience. You will be informed before September 17, 2015.

Erasmus Optical Imaging Centre - OIC - organizes the PhD course

 "Functional Imaging and Super Resolution 

October 26-30, 2015


Provisional program OIC PhD course 2015

A 5 day program, 5 morning lecture sessions, 4 afternoon practical sessions and on Friday afternoon a session dedicated to participants’ presentations of results acquired during the practical sessions. The course will give an overview and increase your knowledge of the rapidly developing advanced imaging methods and how they can support you during your research. An important part is the practical work were you get the opportunity for real handson experience. No prior knowledge is expected, although some basic fluorescent imaging experience will be helpful. The course is intended for PhD students and post-docs and others who need more background in advanced fluorescent imaging and data analysis.

 Registration for PhD students from the MGC is free of costs.


The secretariat PhD program Clinical & Translational Oncology (CTO), UMC Utrecht Centre for Molecular Medicine, likes to announce two courses:


Modern Cancer Pathology Course: 13 - 15 October, 2015

This course covers new technology in cancer diagnostics implemented in the clinic.

Provisional program can be downloaded from the CTO website:

 You can already register for this course via the website of CTO:

 Deadline: 15 September 2015


Clinical Trial Development Course: 3 - 5 November 2015

Organized by dr. Marlies Langenberg and dr. Mirjam Koopman of the UMCU Cancer Center. This course aims to reveal the complexity of issues related to clinical trial design, conduct and analysis. Increasing attention for applicability of basic scientific findings to clinical research poses new demands for PhD students working in medicine related areas and this course will increase the understanding of how to move smoothly from bench-to-bed side.

The course is already open for registration:

Courses organized by MolMed


Photoshop and Illustrator CS6 Workshop for PhD-students and other researchers

8 or 29 September 2015

Hands-on workshop on the Adobe programs Photoshop and Illustrator CS6. These programs are used for image enhancement and for drawing high quality graphs, tables and other figures. These are also freely available at the Erasmus MC on all SOM-pc‘s. These can also be purchased at a very low price via

For more information and registration:


NGS in DNA Diagnostics Course

22-24 September 2015

Course aimed at Genomic Resequencing in a Medical Diagnostic Context, i.e to apply Next Generation Sequencing data as diagnostic tool in the hospital. Lectures will be accompanied with hands-on exploration.

This course is intended for bioinformaticians, researchers and molecular & clinical geneticists. The mixed programme will appeal to all those requiring a solid background in the application of NGS techniques for (routine) genetic diagnosis of a patient. The course will be mainly in English.

For more information and registration:


Indesign CS6 Workshop

30 September 2015

Hands-on workshop on the Adobe program Indesign CS6. This program employs Photoshop and Illustrator and can be used to make high quality posters and even books. The Adobe programs are also freely available at the Erasmus MC on all SOM-pc‘s. These can also be purchased at a very low price via

For more information and registration:

Course Biomedical Research Techniques XIV

2-6 November 2015

This is a popular, basic, annual five-day course on several lab techniques. The program covers:

Day 1: primers and probes, sequencing, SNP-analysis, methylation

Day 2: Microscopy: Quantitative confocal microscopy, Image analysis, FRET, FRAP & computer modeling

Day 3: proteomes, mass spectrometry; Special Discussion Program; site visit facilities labs;

Day 4: (morning) cytotoxicity, ELISA & flow cytometry; (afternoon) RNA, RNA expression arrays, RT PCR, siRNA, data mining

Day 5: Applied Molecular Imaging: MRI, CT, Nuclear, Optical in vivo; Special Research Integrity & site visit proteomics labs

Though full participation is encouraged, it is possible to only participate in part of the course.

More information and registration:


SNP Course XII: SNPs and Human Diseases

16-20 November 2015

The analysis of DNA variations, including Single Nucleotide Polymorphisms (SNPs), is a standard research approach to understand causes of disease, in particular the so-called “complex” diseases such as diabetes, osteoporosis, cancer, Alzheimer disease, etc. The field is changing fast with large scale projects (Human genome, dbSNP, HapMap, 1000genomes, ENCODE) and novel technology being continuously introduced, including Next Generation Sequencing.

Aim: The aim of this course is to give a broad introduction in SNP techniques and applications. The course is primarily organized for PhD students and postdocs of the Erasmus Postgraduate School Molecular Medicine, Nihes, MGC and other research schools. Other participants, e.g., scientists, students, and technicians from other universities in- and outside Netherlands are also welcome.

For more information and registration:


Translational Imaging Workshop by AMIE: From mouse to man

24-27 November 2015

The aim of this 4-day workshop is to give a broad introduction into preclinical and translational Molecular Imaging techniques and their applications in biology and medicine. The program also has demos and gives the possibility to work with one the different techniques: PET-SPECT, CT, MRI, Optical Imaging, and Ultrasound.

This workshop is designed for PhD students and researchers in one of the Erasmus Postgraduate Schools; PhD students and researchers from other universities are also welcome.

For more information and registration:

Courses organised by Boerhaave CME

On the 'Boerhaave CME (Continuing Medical Education)' website several courses for PhD students and other employees of the LUMC are announced:


- Introduction Genetic Epidemiology:  (once a year)

This intensive three day course will provide an introduction in genetic epidemiology. A large part of the day will be devoted to paper and computer exercises. Participants will gain practical experience by analyzing various data sets using SPSS or STATA.


- Design, Management & Analysis of Clinical trials: (once a year)

In this course, issues regarding the design, implementation and analysis of clinical trials will be considered. Topics include randomization and blinding, sample size calculations, flexible designs (interim analyses and stopping rules), cross-over trials, data monitoring and safety committees, data management and of course the statistical analyses based on the design chosen. We will also cover some aspects of reporting the design and outcome of clinical trials in scientific journals as well as Good Research Practice in general.

- Advanced Genetic Association Analysis: (once a year)

This up to date course in genetic association analysis includes now highly relevant topics such as the analysis of imputed genotypes in GWAS, genetic pathway analysis using GWAS data and the statistical analysis of rare variants detected by next generation sequencing. Participants have to bring their own laptop for practicals.

- Regression Analysis: (once a year)

This course considers both theoretical backgrounds and practical aspects of modeling data with regression models. The focus is on linear and logistic regression models, although other models, like Poisson models or non linear regression models for continuous data will also be discussed. All statistical methods are practiced, using SPSS.

- Using R in Data Analysis: (once a year)

R is an environment for statistical computing and graphics. Its flexibility, allied to the fact that it is open-source and free, have made it an ideal repository for implementations of statistical analysis methods, both classic and new. However, it has a steep learning curve, due partly to its using a command-line type of user interface, rather than the usual pull-down menus of most commonly used statistical packages such as SPSS. This 3-day course aims at helping researchers climb this curve, enabling them to perform basic data analysis and graphic displays at the end of the course, as well as giving a platform from which they can deepen their R knowledge later on if necessary.

- Dealing with Conflicting Demands: (once a year)

The life of a scientist presents many conflicting demands in any phase of the scientific career, but certainly in the last phase of a PhD study. The course ‘Dealing with Conflicting Demands’ builds on Dilemma Theory created in the 1980s by Prof. Charles Hampden-Turner (Cambridge, UK). Over the last decade the methodology has been further developed into a practical skill, used by staff of large and small corporations, including private and public research institutions. The skill to reconcile conflicting demands has proven key to being successful in a complex and competitive environment, such as your current and future working life as a scientist or any other professional environment.

- Repeated measurements: (once a year)

The course covers statistical methods to be used in the situation where one or more outcome variables are repeatedly measured in time on the same experimental unit.


- Basic methods and reasoning in biostatistics: (once a year)

The AIO courses in Biostatistics consist of two series: “A:basic” and “B:advanced”. Participants in part B should have followed part A or have acquired the skills trained in part A in another way. Part B as of 2009 consists of a series of separate courses, each dedicated to a specific subject.
Part A is a single one week course:
In this course we will cover basics of biostatistics and the participants will learn how to analyze problems in clinical research using SPSS. Subjects covered are among others: methodology of statistical analysis; causal inference; descriptive statistics; the principle of statistical estimation and testing; cross tabulation and chi-square test; Student t-test and the correspondence with non-parametric counterparts; simple regression and correlation; introduction to analysis of variance; interpretation of observational data; bias and confounding; interaction.


General information:

Download  the booklet with the teaching programme for PhD students, version 2014-2015

For new PhD students: Download the forms for Coaching Group and Teaching Plan

Download MGC bulletin 51 (September 2014),  MGC bulletin 50 (April 2014), 49 (September 2013)

Website of Leiden University on teaching for PhD students: English or Dutch. [Courses on Research management; Career counseling; Academic writing; Writing grants, proposals and beyond; Faster reading and Memory-improvement; Creative thinking; Academic presentation / Presentation of academic work; Orientation in policymaking; Orientation on Management]


The MGC Institutes

Het MGC secretariaat is gevestigd op

de afdeling Humane Genetica, LUMC, Leiden.

TEL 071-5269600; FAX 071-5268284  

Directie secretaris: Dr. M.J.M. Nivard 071-5269605  



De MGC instituten:

Instituut Celbiologie

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. D. Huylebroeck (lid MGC bestuur)


Afd. Humane Genetica

Leiden Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden


hoofd: Prof.Dr. S.M. van der Maarel  (lid MGC bestuur)

Instituut Genetica

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. J.H.J. Hoeijmakers (lid MGC bestuur)

Afd. Humane Genetica

Leids Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden


Prof.Dr. L.H.F. Mullenders (voorzitter MGC bestuur)

LACDR (Leiden/Amsterdam Center for Drug Research) - Toxicology group

Universiteit Leiden

P.O. Box 9502, 2300 RA Leiden


hoofd: Prof.Dr. B. van de Water (lid MGC bestuur)  

Instituut Klinische Genetica

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. R.M.W. Hofstra (secretaris MGC bestuur)

Andere instituten/groepen binnen het MGC

Moleculaire Celbiologie (Prof. Dr. H.J. Tanke & Prof. Dr. A.K. Raap, Prof. Dr. J. Noordermeer & Dr. L. Fradkin, Prof. Dr. R. Hoeben, Prof. Dr. J.A. Maassen, Prof. Dr. P. ten Dijke)

Neurologie, groep neurogenetica, LUMC (Prof. Dr. R.A.C. Roos, Prof. Dr. J.J.G.M. Verschuuren, Prof. Dr. M.D. Ferrari)

Huid- en geslachtsziekten, groep erfelijke melanomen, LUMC (Prof. R. Willemze, Prof. Dr. W. Bergman, Dr. F. de Gruijl, Dr. N.A. Gruis)

Pathologie: moleculaire tumorpathologie, LUMC (Prof. Dr. P.C.W. Hogendoorn, Prof. J.V.M.G. Bovee, Prof. Dr. J. Morreau, Prof. Dr. P. Devilee)

Medische Statistiek, LUMC (Prof. Dr. T. Stijnen, Prof. Dr. P.E. Slagboom)

Anatomie en Embryologie, LUMC (Prof. Dr. C.L. Mummery)

Erasmus Optical Imaging Centre (OIC), Department of Pathology, Erasmus MC (Prof. Dr. A. B. Houtsmuller)

Kinderheelkunde, Ontwikkelingsbiologie groep, Erasmus MC (Prof. Dr. D. Tibboel)

Genetische Epidemiologie, Erasmus MC (Prof. Dr. C.M. van Duijn)

Afd. Voortplanting en Ontwikkeling, Erasmus MC (Prof. Dr. J.A. Grootegoed)

Forensische Moleculaire Biologie, Erasmus MC (Prof. Dr. M. Kayser)

Bioinformatica, Erasmus MC (Prof. Dr. P. van der Spek)

Biochemie, Erasmus MC (Prof. Dr. P. Verrijzer)


   [n.b. verbeteringen voor deze lijst gaarne doorgeven aan het secretariaat]




























Revised: September 25, 2015