- MGC -        

The Centre is an initiative of the Erasmus Medical Center and the Leiden University Medical Center


25th-anniversary of the MGC - October 4, 2013



To conclude the 25th Anniversary Year we will organize a special edition of the MGC symposium on Friday, September 19, 2014 at Engels, Rotterdam


Keynote lecture will be given by James Briscoe, NIMR, Mill Hill


The evening will be accompanied by party Band Go Yellow! (


Registration for MGC Symposium and/or Dinner


 Program MGC symposium


On the registration form you will find the possibility to register for both Symposium and Dinner Party or for one of the two activities. We happily welcome people who want to attend the Dinner Party only.

Deadline for registration September 5, 2014


Symposia & Meetings:

Het lectoraat Analysetechnieken in de Life Science van Avans Hogeschool ontwikkelt en geeft cursussen op het gebied van biomedische laboratorium technieken voor bedrijven, universiteiten en instellingen. In het najaar zijn dat:

Medische Immunologie: Cursus data: 10 avonden; elke donderdag vanaf 18 september tot 27 november. Tijden: alle avond van 19.00u - 21.30 met uitzondering van de laatste avond 18.30-21.30. Prijs: 950 euro. Locatie: Erasmus MC Rotterdam​ 
Cursus data: 7, 14 en 28 oktober. Tijden: 16.00u – 18.45u. Prijs: 600 euro. Locatie: Erasmus MC Rotterdam

To simplify the search for an interesting meeting: .

This website gives an overview of conferences organized in all aspects of biology. It is open source so everybody can not only find but also add their meeting. It’s launched in April, 2012 and already contains over 400 conferences, a number that’s increasing every day.

All the added meetings are categorized so you can search both by keyword and category.

PCDI - Postdoc Career Development Initiative - is an organisation that aims at improving awareness of career planning and opportunities among postdocs, PhD students and their employers. We bring together scientists, universities and key players in the life science industry.



MGC Course Programme

You can enrol now for the following courses:

Course 'From Molecular Pathogenesis to Targeted Therapy'

27 - 31 October, 2014

LUMC, room V3-26/30 (building 3)

Provisional program


Organizers: Peter ten Dijke en Hans ten Dam, Department of Molecular Cell Biology, LUMC

The aim of this course is to give an overview of intracellular signalling processes that are activated by hormones, cytokines and growth factors, as well as state-of-the-art technology used to study signal transduction in vivo and in vitro. Teaching will occur by state-of-the-art lectures and interactive tutorial.

For PhD students from MGC, LUMC and Erasmus MC the course is free of cost for all other people from the academic world the course fee is 250 euro. We only have facilities to accommodate 18 participants next to the 18 FOS students. Should the course be oversubscribed, then places will be allocated on a first come, first serve basis.

Deadline for registration October 15, 2014.


Courses organized by MolMed



* Photoshop and Illustrator CS6 Workshop for PhD-students and other researchers

September – October 2014

One full day hands-on workshop on the Adobe programs Photoshop and Illustrator CS6. These programs are used for image enhancement and for drawing high quality graphs, tables and other figures. Both programs are freely available at the Erasmus MC on all Som-pc‘s. Both programs can be purchased for a low price via

For more information and registration:


*Indesign CS6 Workshop for PhD-students and other researchers

September – October 2014

Adobe InDesign CS6  program is very handy for making posters and a thesis. Indesign is compatible with Illustrator and Photoshop.

For more information and registration:


Research management for Postdocs

8 & 29 October 2014

In two days four different topics will be dealt with: Time management, Negotiating, Giving Feedback, and Project Management.

A homework assignment is also part of this interactive and very useful course.

Due to the practical nature of this course, we can only allow 12 participants into the course. Full course participation is also a requirement.

For more information and registration:


Course Biomedical Research Techniques XIII

13 - 17 October 2014

This is an  popular, basic, annual five-day course on several lab techniques. The program covers:

Day 1: primers and probes, sequencing, SNP-analysis, methylation

Day 2: RNA, RNA expression arrays, RT PCR, siRNA, data mining

Day 3: site visit DNA/RNA labs; proteomes, mass spectrometry

Day 4: (morning) ELISA, cytotoxicity, flow cytometry & phage antibody display; (afternoon) Microscopy: Quantitative confocal microscopy, Image analysis, FRET, FRAP & computer modeling

Day 5: Applied Molecular Imaging: MRI, CT, Nuclear, Optical in vivo;; site visit proteomics labs

Though full participation is encouraged, it is possible to only participate in part of the course.

More information and registration:


         * NGS in DNA Diagnostics Course

         28-30 October 2014

VKGL/VKGN ‘NGS in DNA diagnostics’ is a course aimed at Genomic Resequencing in a Medical Diagnostic Context, i.e to apply Next Generation Sequencing data as diagnostic tool in the hospital. Lectures will be accompanied with hands-on exploration.

This course is intended for bioinformaticians, researchers and molecular & clinical geneticists. The mixed programme will appeal to all those requiring a solid background in the application of NGS techniques for (routine) genetic diagnosis of a patient. The course will be mainly in English. Accreditation will be filed for at VKGL and VKGN.

For more information and registration:


 Translational Imaging Workshop by AMIE: From mouse to man

11 – 14 November 2014

The programme Applied Molecular Imaging at Erasmus MC (AMIE) provides a platform for scientists interested in imaging technology and molecular imaging in general. The aim of this 4-day workshop is to give a broad introduction into preclinical and translational Molecular Imaging techniques and their applications in biology and medicine. The Workshop features demos of different techniques and the possibility to perform an experiment on one of the techniques.

This workshop is designed for PhD-students and researchers in one of the Erasmus Postgraduate Schools, but PhD students and researchers from other universities are also welcome.

More information and registration:


Research management for PhD-students

12 & 26 November 2014

Popular 2-days course on research management skills for PhD-students: - Time management; - Negotiating; - Yearly reviews (‘jaargesprekken’); and - Project management.

Full course attendance is necessary. There is place for 12 participants.

For more information and registration:


SNP Course XI: SNPs and Human Diseases

17 - 21 November 2014

Annual five-days course on SNP and Complex Diseases, including hands-on computer practicals.

For participation, basic knowledge of the central molecular biological is required. This can be obtained at the basic human Genetics course: Genetics for dummies.

For more information and registration:



* The Basic and Translational Oncology Course will be organized in the week of 3 February 2015.

This course provides a comprehensive introduction to the field of translational cancer research. This course is meant for PhD students and postdocs from MolMed and MGC, but others are welcome as well. This program features several keynote from NCI and elsewhere.

Once the programs of these course are known, we will put them course on our website and set them open for registration.


Courses organised by Boerhaave CME

On the 'Boerhaave CME (Continuing Medical Education)' website several courses for PhD students and other employees of the LUMC are announced:


- Introduction Genetic Epidemiology:  (once a year)

This intensive three day course will provide an introduction in genetic epidemiology. A large part of the day will be devoted to paper and computer exercises. Participants will gain practical experience by analyzing various data sets using SPSS or STATA.


- Design, Management & Analysis of Clinical trials: (once a year)

In this course, issues regarding the design, implementation and analysis of clinical trials will be considered. Topics include randomization and blinding, sample size calculations, flexible designs (interim analyses and stopping rules), cross-over trials, data monitoring and safety committees, data management and of course the statistical analyses based on the design chosen. We will also cover some aspects of reporting the design and outcome of clinical trials in scientific journals as well as Good Research Practice in general.

- Advanced Genetic Association Analysis: (once a year)

This up to date course in genetic association analysis includes now highly relevant topics such as the analysis of imputed genotypes in GWAS, genetic pathway analysis using GWAS data and the statistical analysis of rare variants detected by next generation sequencing. Participants have to bring their own laptop for practicals.

- Regression Analysis: (once a year)

This course considers both theoretical backgrounds and practical aspects of modeling data with regression models. The focus is on linear and logistic regression models, although other models, like Poisson models or non linear regression models for continuous data will also be discussed. All statistical methods are practiced, using SPSS.

- Using R in Data Analysis: (once a year)

R is an environment for statistical computing and graphics. Its flexibility, allied to the fact that it is open-source and free, have made it an ideal repository for implementations of statistical analysis methods, both classic and new. However, it has a steep learning curve, due partly to its using a command-line type of user interface, rather than the usual pull-down menus of most commonly used statistical packages such as SPSS. This 3-day course aims at helping researchers climb this curve, enabling them to perform basic data analysis and graphic displays at the end of the course, as well as giving a platform from which they can deepen their R knowledge later on if necessary.

- Dealing with Conflicting Demands: (once a year)

The life of a scientist presents many conflicting demands in any phase of the scientific career, but certainly in the last phase of a PhD study. The course ‘Dealing with Conflicting Demands’ builds on Dilemma Theory created in the 1980s by Prof. Charles Hampden-Turner (Cambridge, UK). Over the last decade the methodology has been further developed into a practical skill, used by staff of large and small corporations, including private and public research institutions. The skill to reconcile conflicting demands has proven key to being successful in a complex and competitive environment, such as your current and future working life as a scientist or any other professional environment.

- Repeated measurements: (once a year)

The course covers statistical methods to be used in the situation where one or more outcome variables are repeatedly measured in time on the same experimental unit.


- Basic methods and reasoning in biostatistics: (once a year)

The AIO courses in Biostatistics consist of two series: “A:basic” and “B:advanced”. Participants in part B should have followed part A or have acquired the skills trained in part A in another way. Part B as of 2009 consists of a series of separate courses, each dedicated to a specific subject.
Part A is a single one week course:
In this course we will cover basics of biostatistics and the participants will learn how to analyze problems in clinical research using SPSS. Subjects covered are among others: methodology of statistical analysis; causal inference; descriptive statistics; the principle of statistical estimation and testing; cross tabulation and chi-square test; Student t-test and the correspondence with non-parametric counterparts; simple regression and correlation; introduction to analysis of variance; interpretation of observational data; bias and confounding; interaction.


General information:

Download  the booklet with the teaching programme for PhD students, version 2014-2015

For new PhD students: Download the forms for Coaching Group and Teaching Plan

Download MGC bulletin 51 (September 2014),  MGC bulletin 50 (April 2014), 49 (September 2013)

Website of Leiden University on teaching for PhD students: English or Dutch. [Courses on Research management; Career counseling; Academic writing; Writing grants, proposals and beyond; Faster reading and Memory-improvement; Creative thinking; Academic presentation / Presentation of academic work; Orientation in policymaking; Orientation on Management]


The MGC Institutes

Het MGC secretariaat is gevestigd op

de afdeling Humane Genetica, LUMC, Leiden.

TEL 071-5269600; FAX 071-5268284  

Directie secretaris: Dr. M.J.M. Nivard 071-5269605  



De MGC instituten:

Instituut Celbiologie

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. D. Huylebroeck (lid MGC bestuur)


Afd. Humane Genetica

Leiden Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden


hoofd: Prof.Dr. S.M. van der Maarel  (lid MGC bestuur)

Instituut Genetica

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. J.H.J. Hoeijmakers (lid MGC bestuur)

Afd. Humane Genetica

Leids Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden


Prof.Dr. L.H.F. Mullenders (voorzitter MGC bestuur)

LACDR (Leiden/Amsterdam Center for Drug Research) - Toxicology group

Universiteit Leiden

P.O. Box 9502, 2300 RA Leiden


hoofd: Prof.Dr. B. van de Water (lid MGC bestuur)  

Instituut Klinische Genetica

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. R.M.W. Hofstra (secretaris MGC bestuur)

Andere instituten/groepen binnen het MGC

Moleculaire Celbiologie (Prof. Dr. H.J. Tanke & Prof. Dr. A.K. Raap, Prof. Dr. J. Noordermeer & Dr. L. Fradkin, Prof. Dr. R. Hoeben, Prof. Dr. J.A. Maassen, Prof. Dr. P. ten Dijke)

Neurologie, groep neurogenetica, LUMC (Prof. Dr. R.A.C. Roos, Prof. Dr. J.J.G.M. Verschuuren, Prof. Dr. M.D. Ferrari)

Huid- en geslachtsziekten, groep erfelijke melanomen, LUMC (Prof. R. Willemze, Prof. Dr. W. Bergman, Dr. F. de Gruijl, Dr. N.A. Gruis)

Pathologie: moleculaire tumorpathologie, LUMC (Prof. Dr. P.C.W. Hogendoorn, Prof. J.V.M.G. Bovee, Prof. Dr. J. Morreau, Prof. Dr. P. Devilee)

Medische Statistiek, LUMC (Prof. Dr. T. Stijnen, Prof. Dr. P.E. Slagboom)

Anatomie en Embryologie, LUMC (Prof. Dr. C.L. Mummery)

Erasmus Optical Imaging Centre (OIC), Department of Pathology, Erasmus MC (Prof. Dr. A. B. Houtsmuller)

Kinderheelkunde, Ontwikkelingsbiologie groep, Erasmus MC (Prof. Dr. D. Tibboel)

Genetische Epidemiologie, Erasmus MC (Prof. Dr. C.M. van Duijn)

Afd. Voortplanting en Ontwikkeling, Erasmus MC (Prof. Dr. J.A. Grootegoed)

Forensische Moleculaire Biologie, Erasmus MC (Prof. Dr. M. Kayser)

Bioinformatica, Erasmus MC (Prof. Dr. P. van der Spek)

Biochemie, Erasmus MC (Prof. Dr. P. Verrijzer)


   [n.b. verbeteringen voor deze lijst gaarne doorgeven aan het secretariaat]




























Revised: September 17, 2014