- MGC -        

The Centre is an initiative of the Erasmus Medical Center and the Leiden University Medical Center



Symposia & Meetings:

Postdoctoral position available at Columbia University Medical Center in the city of New York.

The Ciccia laboratory is located in the state-of-the-art Irving Cancer Research Center. The Ciccia laboratory studies the cellular pathways that maintain genomic stability to prevent the development of breast and ovarian cancer (Taglialatela et al, Molecular Cell, 2017). Furthermore, the Ciccia laboratory investigates the mechanisms of CRISPR-mediated gene editing and develops novel CRISPR-dependent technologies (Billon et al, Molecular Cell, 2017; Information about current projects of the Ciccia laboratory can be found at

To simplify the search for an interesting meeting:

29-30 November and 1 December 2017 course Clinical Trial Development organized by the CTO program together with the department of Medical Oncology of the UMC Utrecht Cancer Center.

There are only a few places left to attend this course! After that they will be working with a reserve list. Please use the following link for further information about the program and registration:

PCDI - Postdoc Career Development Initiative - is an organisation that aims at improving awareness of career planning and opportunities among postdocs, PhD students and their employers. We bring together scientists, universities and key players in the life science industry.


MGC Course Programme

You can enrol now for the following courses:

Course 'Practical Linux'

LUMC, Building 1, J1-84

6 December, 2018

Registration form


This short and concise hands-on course, designed especially for researchers, will teach you how to effectively use the Linux command line interface. After completing this course, attendees will be able to swiftly start using Linux both on a server, e.g., the LUMC Shark cluster, as well as on your personal computer.  The lessons are interactive and will take place in a location with computer facilities.

Goals: - Basic understanding of operating systems - Understand and navigate the filesystem - Obtain information about files and directories - Manipulate, i.e., create, delete, move, and rename files and directories - Inspect and edit file content - Gather disk storage information - Search for and within files - Manage file and directory access permissions - Connect to other computers

This year the course will be given on the following date:  6 December (13:00-17:30).

Course is free of charge. Please indicate on the registration form for which date you will subscribe. 



By completing this course you will be able to join the following courses:
- Introduction to the Shark cluster
- Code and Data Management with Git
- Scripting for Life Science Researchers

- Python Programming
There is a maximum of 18 places for each edition of the course. Should an edition of the course be oversubscribed then places will be allocated based on a first-come

first-serve basis.

Workshop  “How to make a video about your own research”.

LUMC, Building 2

15 (afternoon) and 29 November (half day) and 13 December (afternoon), 2017

This workshop is a new initiative of the MGC and will be offered to you for free. There are 8 places available and you will work in duo’s. There is a preference for duo’s working at the same research group, obviously because both participants can benefit from the movie, but this is not a prerequisite. Therefore, you can either sign up for this workshop as a duo or you can sign up as an individual (not knowing if you can use the movie afterwards).

This first edition is already fully booked but if you are interested you can send an email to


Animated Science: explaining research in a short video

Would you like to know how to make an explanation video about your own research?

Bruno van Wayenburg, animator and science writer, and Astrid Smit, trainer at De Perskamer and science writer, will provide you with the tools and tricks to make these videos.

The workshop consists of three (half) days

On the first day of this workshop (afternoon only), Bruno and Astrid will tell you about science communication and how to prepare an explanation video (from storyboard and script to recording a voiceover, drawing illustrations, editing and sound-effects). On the second day of the workshop (whole day) , you will be starting on your own animation. Afterwards you get two weeks to finish your video and present your video to the rest of the group on the third day of the workshop (afternoon only).


Course 'Safely working in the Laboratory'

8 January, 2018 in room J1-116, LUMC - Building 1

Course is fully booked


A 'one day' course that is intended to refresh the memory and to supplement courses that may have been followed earlier. The following points will be addressed: safe microbiological techniques; radiation; toxic and carcinogenic agents; physical strain, transport and disposal hazardous waste.

This course is mandatory for all PhD students working within the MGC and is free of charge on condition that you will be present during the entire course.. This edition of the course will be in English; the Dutch version is expected to be given in spring 2018.

Course 'Technology Facilities'


 12, 14, 15 and 16 February, 2018 (note: 13 February no course day!)

LUMC (except on 15 February: Gorlaeus Laboratories)


Program edition 2017



The course will deal with four topics:

Day 1: 12 February - Genomics and Transcriptomics

     Organizers: Dr. W. van IJcken, Erasmus MC, Rotterdam, and Dr. S. Kloet, and Prof. Dr. J. den Dunnen, LUMC, Leiden

Day 2: 14 February - Proteomics

    Organizers: Dr. J. Demmers, Erasmus MC, Rotterdam and Dr. P. Hensbergen, LUMC, Leiden

Day 3: 15 February – Metabolomics

    Organizer: Prof. Dr. T. Hankemeier, Leiden Academic Centre for Research (LACDR) - division Toxicology, University Leiden

Day 4: 16 February – Live cell imaging (half day)

     Organizer: Dr. G. van Cappellen and Prof. Dr. A. B. Houtsmuller, Erasmus MC, Rotterdam


The course is directed primarily at PhD students who just started their research or are not familiar with the different topics but other participants are welcome too. One can also subscribe for individual days.

There is a minimum of 14 and a maximum of 40 places. Deadline for registration 31 January, 2018.

The course is free of charge for all personnel from MGC institutes. Participants from outside these institutes pay €400 including lunches. Registration costs for a single day is €100. In case of no show participants from the MGC institutes will be charged 50 euro, other participants have to pay the full price.

Course 'Introduction to Cytoscape'

18 April, 2018 in room J1-84, LUMC - Building 1

Program edition April 2017



The aim of this course is to introduce the Cytoscape software platform for visualizing complex networks and integrating omics (e.g. gene expression, proteomics and metabolomics) data. It will be the third time that this course is organized by MGC in collaboration with Center for Proteomics and Metabolomics, LUMC.

There is a maximum of 20 places. If the course will be oversubscribed a selection will be made by the course coordinator. People not selected for this edition will be selected with priority for next edition.

The course is free of charge for all personnel from MGC institutes and from the Center for Proteomics and Metabolomics (LUMC). Participants from outside these institutes pay €150 including lunch.


Course 'Genome Maintenance and Cancer'

19-20 March, 2018



 Program 2018  


Preservation of genetic information (DNA) is of prime importance to all living systems. The aim of the course is to familiarize participants with the mechanisms that are involved in maintaining genome stability. In the environment humans are exposed to chemical agents and radiation, which threaten the integrity of the genetic material leading to risks for the induction of cancer and congenital malformation. To withstand the harmful effects of DNA damage and to maintain genome integrity, cells are equipped with an intricate network of DNA damage response pathways. Key players in these processes are protein complexes involved in DNA replication, DNA repair and chromosome segregation as well as regulators of the cell cycle and cell death.

This course will provide an up to date insight in the chain of reactions from exposure to the ultimate consequences. Lectures will deal with the basic principles of several cell biological aspects such as DNA damage formation, signalling pathways, DNA repair and mutation formation.  A few lectures will deal with more applied research.                


There is a minimum of 14 and a maximum of 35 places. Deadline for registration 5 March, 2018.

The course is free of charge for all personnel of MGC associated institutes and OOA (VUMC, AMC, NKI departments), CTO (UMC Utrecht), and RIMLS/RIHS (Radboud UMC) associated departments. Participants from outside these organizations pay € 200 for this course. In case of no show participants from the MGC, OOA, CTO and RIMLS/RIHS  institutes will be charged 50 euro, other participants have to pay the full price.

Course ‘Epigenetic Regulation in Health and Disease'

24-25 May, 2018

Erasmus MC


Program edition 2016


The course aims to introduce students to epigenetic technologies by providing an overview of the state-of-the-art chromatin and gene regulation studies in The Netherlands. The course consists of lecture sessions in the morning and in the afternoon.

Some of the topics induced are: genome wide methylation profiling, genetic and epigenetic pathways in health and disease, transcription factors, chromatin remodelling, chromatin and the DNA damage response, X-inactivation and stem cells.


There is a minimum of 14 and a maximum of 100 places.

The course is free of charge for all personnel of MGC associated institutes and OOA (VUMC, AMC, NKI departments), CTO (UMC Utrecht), and RIMLS/RIHS (Radboud UMC) associated departments. Participants from outside these organizations pay € 200 for this course. In case of no show participants from the MGC, OOA, CTO and RIMLS/RIHS  institutes will be charged 50 euro, other participants have to pay the full price.


Courses organized by Research School OOA (Oncology Graduate School Amsterdam)

Please check the website ( for more information and registration.

Courses organized by Research School CTO (Clinical and Translational Oncology, UMC Utrecht)

CTO Course Clinical Trial Development, 29-30 November and 1 December 2017.

Please use the following link for further information about the program and registration (which will be provided later):

Courses organized by MolMed


SNP Course XIV: SNPs and Human Diseases – new!

13 – 17 November, 2017

The analysis of DNA variations, including Single Nucleotide Polymorphisms (SNPs), is a standard research approach to understand causes of disease, in particular the so-called “complex” diseases such as diabetes, osteoporosis, cancer, Alzheimer disease, etc. The field is changing fast with large scale projects (Human genome, dbSNP, HapMap, 1000genomes, ENCODE) and novel technology being continuously introduced, including Next Generation Sequencing. The aim of this course is to give a broad introduction in SNP techniques and applications.

For more information and registration:


Erasmus MC Cancer Institute Research Day – new

30 November, 2017
We organize the Cancer Institute Research Day (former mentioned Daniel den Hoed Day), from 10.00 until 15.00. The day is organized by MolMed in close cooperation with the Erasmus MC Cancer Institute.
For more information and registration:


Basic Course on 'R'

18 - 22 December, 2017

Learning objectives: after following this course participants will be able to use R in their everyday data manipulation and statistical analysis tasks. Moreover, they will learn the basic structure of the language in such a way that it will become easier to follow more advanced topics such as the Bioconductor or advanced R programming. This course is not about statistics. However, since R is a statistical programming language some basic knowledge of statistical concepts is required. During the course the concepts needed will be briefly summarized

For more information and registration:


Microscopic Image Analysis: From Theory to Practice

29 – 30 January, 2018

During this course, the participant will 1) obtain a deeper theoretical understanding of image analysis methods, and 2) obtain practical experience with image analysis software tools (in particular ImageJ) and learn how to use them intelligently, on their own computer.

For more information and registration:


Ensembl Workshop – definitive date

13 - 14 February, 2018

This two day’s workshop offers participants the possibility of gaining lots of hands-on experience in the use of the Ensembl genome browser but also provides them with the necessary background information. You can learn about gene, homology, variation, and regulation data in Ensembl and how to access them, as well as the suite of tools we develop and maintain to process and analyse your own data. The workshop is primarily targeted at wetlab researchers. An experienced teacher of the European Bioinformatics Institute will give this workshop

For more information and registration: 


Courses organised by Boerhaave CME or others

On the 'Boerhaave CME (Continuing Medical Education)' website several courses for PhD students and other employees of the LUMC are announced:


- Introduction Genetic Epidemiology:  (once a year)

- Design, Management & Analysis of Clinical trials: (once a year)

- Advanced Genetic Association Analysis: (once a year)

- Regression Analysis: (once a year)

- Using R in Data Analysis: (once a year)

- Dealing with Conflicting Demands: (once a year)

- Repeated measurements: (once a year)

- Basic methods and reasoning in biostatistics: (once a year)


PhD course Introduction to Neuroimaging  - Leiden
30 Oct. - 17 Nov. 2017
Part-time program (mornings only) including: Basics of MRI, CT, PET and optical imaging; Advanced methodologies, such as fMRI, ASL, DTI and ultra-high field MRI; Applications in neurology and neuroscience, in humans and animal models; Latest developments.
For more information please contact Dr. Louise van der Weerd by e-mail:




General information:

Download the booklet with the teaching programme for PhD students, version 2016-2017

Download MGC bulletin 52  (september 2015)

Website of Leiden University on teaching for PhD students: English or Dutch. [Courses on Research management; Career counseling; Academic writing; Writing grants, proposals and beyond; Faster reading and Memory-improvement; Creative thinking; Academic presentation / Presentation of academic work; Orientation in policymaking; Orientation on Management]


The MGC Instituten

Het MGC secretariaat is gevestigd op

de afdeling Humane Genetica, LUMC, Leiden.

TEL 071-5269600; FAX 071-5268284  

Directie secretaris: Dr. M.J.M. Nivard 071-5269605  



De MGC instituten:

Afdeling Humane Genetica

Leiden Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden


hoofd: Prof.Dr. S.M. van der Maarel  (voorzitter MGC bestuur)

Afdeling Celbiologie

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. D. Huylebroeck (lid MGC bestuur)

Afdeling Moleculaire Celbiologie

Leiden Universitair Medisch Centrum

Postbus 9600, 2300 RC Leiden


hoofd: Prof.Dr. H.J. Tanke (lid MGC bestuur)

Afdeling Klinische Genetica

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. R.M.W. Hofstra (secretaris MGC bestuur)

Afdeling Moleculaire Genetica

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. R. Kanaar (lid MGC bestuur)

LACDR (Leiden Academic Centre for Drug Research) - Research Division Drug Discovery and Safety

Universiteit Leiden

P.O. Box 9502, 2300 RA Leiden


hoofd: Prof.Dr. B. van de Water (lid MGC bestuur)  

  Afdeling Ontwikkelingsbiologie,

Erasmus MC - Rotterdam

Postbus 2040, 3000 CA Rotterdam


hoofd: Prof.Dr. J.H. Gribnau (lid MGC bestuur)


Andere afdelingen/groepen binnen het MGC

Biochemie, Erasmus MC (Prof. Dr. P. Verrijzer)

Pathologie, onderzoeksgroep Bioinformatica, Erasmus MC (Prof. Dr. P. van der Spek)

Pathologie, Erasmus Optical Imaging Centre (OIC), Erasmus MC (Prof. Dr. A. B. Houtsmuller)

Genetische Epidemiologie, Erasmus MC (Prof. Dr. C.M. van Duijn)

Genetische Identificatie, Erasmus MC (Prof. Dr. M. Kayser)

Kinderheelkunde, Erasmus MC (Prof. Dr. D. Tibboel)

Anatomie en Embryologie, LUMC (Prof. Dr. C.L. Mummery)

 Huid- en geslachtsziekten, groep erfelijke melanomen, LUMC (Prof. Dr. W. Bergman)

Klinische Genetica, LUMC (Prof. Dr. C.J. van Asperen)

Moleculaire Epidemiologie, LUMC (Prof. Dr. P.E. Slagboom)

Pathologie: moleculaire tumorpathologie, LUMC (Prof. V.T.H.B.M. Smit, Prof. Dr. P.C.W. Hogendoorn, Prof. J.V.M.G. Bovee, Prof. Dr. J. Morreau, Prof. Dr. P. Devilee)


   [n.b. verbeteringen voor deze lijst gaarne doorgeven aan het secretariaat]




























Revised: december 12, 2017